Hiring Fully Remote Employees Outside the US as a US-Based Company

Attention to all US-based recruiters! I’m curious about the challenges of hiring individuals who want to work for a US company while being fully remote and located outside the US.

For instance, consider a German citizen living in Peru and working for a US-based firm while operating in the same time zone.

What specific challenges might arise from hiring someone in this situation compared to a candidate based in the US?

Thank you for your insights!